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Table 1 Definitions of trial outcomes, the corresponding intervention sub-component and the trial period when all sub-components were available

From: eRegMat – a digital registry for improved quality of antenatal care: a cluster-randomized trial in a rural area in Bangladesh

Outcome

Definition

Intervention with direct effect

Implementation period with all sub-components available

Timely attendance at eligible ANC visits

Timely ANC attendance at recommended visitsa

Targeted Client Communication via SMS: ANC appointment reminders

Health worker clinical decision support

Feedback dashboard with action items

December 2019 – June 2020

Screening and management of hypertension in pregnancy

Screening with blood pressure measurement at recommended ANC visitsa and blood pressure within normal range; and appropriate management if hypertension is detected at any timeb

Health worker clinical decision support

Feedback dashboard with action items

October 2018 – June 2020

Timely first antenatal care visit

ANC visit at or before 16 weeksc

Targeted client communication via SMS: ANC visit appointment reminder for first ANC visit

July 2019 – June 2020

High riskd women successfully referred to a skilled provider for additional care

Additional care received among those referred for severe anemia, hypertension, or diabetes during pregnancy

Health worker clinical decision support

Targeted client communication via SMS: Referral reminders, high risk, facility delivery reminders

July 2019 – June 2020

Facility delivery

Health facility delivery among those that should deliver in a health facility according to identified risk factors during pregnancy

Health worker clinical decision support

Targeted client communication via SMS: facility delivery reminders

July 2019 – June 2020

Perinatal mortality and severe perinatal morbidities among all and among those with any risk factors identifiedd

Mortality and morbidities in the perinatal periode among all enrolled participants and among those with a risk factor identified in the woman during pregnancy

Health worker clinical decision support

Feedback dashboard with action items

Targeted client communication via SMS: ANC appointment reminders, referral reminders, facility delivery reminders

December 2019 – June 2020

Severe postpartum anemia

Severe anemia in the postpartum period (hemoglobin 7 g/dl)

Health worker clinical decision support

Feedback dashboard with action items

Targeted client communication via SMS: ANC appointment reminders, Referral reminders, high risk, facility delivery reminders

December 2019 – June 2020

  1. ANC Antenatal care
  2. aRecommended antenatal care visits and gestational age windows for analysis: 16 weeks (≤ 17 + 6 weeks), 24 + 0 to 28 + 6 weeks, 32 weeks (31 + 0 to 33 + 6 weeks), and 36 weeks (35 + 0 to 37 + 6 weeks)
  3. bDefined as systolic blood pressure ≥ 140 mm Hg and diastolic blood pressure ≥ 90 mm Hg at ≥ 20 weeks of gestation, chronic hypertension if detected < 20 weeks
  4. cDefined as an ANC visit ≤ 17 + 6 weeks
  5. dRisk pregnancies were generated automatically in the eRegistry based on the documentation of certain conditions according to the national guidelines in Bangladesh
  6. eDefined as having a stillbirth, early neonatal death, very preterm birth, very low birthweight baby, a neonate that was severely ill or hospitalized in the first week of life